Food and activity advocates in New York City are collaborating to develop a comprehensive and long-term plan for making changes to food and activity environments, particularly in high-need neighborhoods. Funded by the W.K. Kellogg Foundation, the New York City Food and Fitness Partnership is increasing access to healthy food in communities and enhancing opportunities for active living.

The Boston Indicators Project, initiated in 1997 with its first formal report released in 2000, issues biennial indicator reports with measures of progress in sectors that are directly related to social determinants of health and conditions in Boston's communities that either promote or detract from the health of residents.

In Western New York State's Monroe County, like in other New York counties, the rate of childhood lead poisoning was alarming, especially among low-income children. In response, the Coalition to Prevent Childhood Lead Poisoning was established in 2000 with a mission to "end childhood lead poisoning in Monroe County in 2010". Recognized by then-U.S. Senator Hilary Rodham Clinton as a "national model" for reducing childhood lead poisoning, the county coalition's efforts have cut childhood lead poisoning rates by 72% in eight years.

African Americans in Louisville, Kentucky, as in the rest of the U.S., experience greater health inequities compared to other racial and ethnic groups. This population, in particular, disproportionately experiences illness, violence-related injuries and premature death. In response, the Louisville Metro Department of Public Health and Wellness's Center for Health Equity is tracing the pathway from illness and injury to the community conditions, norms and root factors that lead to poor health and inequity in the first place. By building capacity among historically disenfranchised neighborhoods, CHE is leading an urban movement to promote equal opportunities for health and safety.

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